A Prosepective Randomized Trial of Antibiotic Duration in Post-Appendectomy Abscess

October 21, 2021

Post-operative abscess is the most common complication following appendectomy for perforated appendicitis.  There is wide variation in the duration of antibiotic administration following source control of the abscess.  The purpose of this study is to evaluate the duration of antibiotic therapy in patients who have undergone abscess drainage and identify the minimum length of time necessary to treat.  This study is a randomized controlled trial comparing the impact 4-day vs 8-day antibiotic regimens on abscess formation, length of stay, treatment cost and burden to families.